Target detail
DNMT3A
DNA methyltransferase 3 alpha
Data: Live structured evidence (Supabase)
Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).
Display name: DNA methyltransferase 3 alpha
Aliases: DNMT3A, DNA methyltransferase 3 alpha
Type / organism: protein_coding · Homo sapiens
Source: opentargets · ENSG00000119772
Index freshness: last_synced_at 2026-05-15T19:38:31.426+00:00 · updated 2026-05-15T19:38:31.997596+00:00
Limitations & build flags
- Read-only structured navigator
- No clinical outcome benefit inferred
- Trial presence does not imply success
- Drug identity may require normalization
- Terminated/withdrawn trials must remain visible
This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.
Connectors represented in loaded rows for DNMT3A. Empty groups mean no matching rows — not a claim about biology or clinical use.
- Open TargetsLive when indexed
Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).
- ChEMBLLive when indexed
Drug–target and related enrichment rows when operators run enrich:chembl (server/CLI only).
Rows from disease_target_evidence for this symbol.
glioblastoma
genetic_association,literature · opentargets
Drug records tied via drug_targets — mechanistic linkage only.
AZACITIDINE
chembl1489
CHEMBL589775
chembl589775
DECITABINE
chembl1201129
CHEMBL1818029
chembl1818029
CHEMBL1818031
chembl1818031
CHEMBL1818033
chembl1818033
CHEMBL1818030
chembl1818030
CHEMBL1818032
chembl1818032
CHEMBL1818034
chembl1818034
CHEMBL1818035
chembl1818035
CHEMBL2204995
chembl2204995
CHEMBL1818138
chembl1818138
CHEMBL167773
chembl167773
CHEMBL353650
chembl353650
CHEMBL3134245
chembl3134245
CHEMBL2204997
chembl2204997
CHEMBL2204998
chembl2204998
CHEMBL3134234
chembl3134234
CHEMBL3134246
chembl3134246
CHEMBL3134243
chembl3134243
CHEMBL3134241
chembl3134241
CHEMBL597112
chembl597112
CHEMBL3414633
chembl3414633
CHEMBL3126646
chembl3126646
CHEMBL3358015
chembl3358015
CHEMBL3414632
chembl3414632
CHEMBL2336409
chembl2336409
CHEMBL3577854
chembl3577854
CHEMBL3605943
chembl3605943
S-ADENOSYLHOMOCYSTEINE
chembl418052
CHEMBL3605942
chembl3605942
CHEMBL3605941
chembl3605941
CHEMBL3605939
chembl3605939
CHEMBL3605937
chembl3605937
CHEMBL3605935
chembl3605935
CHEMBL3605940
chembl3605940
CHEMBL3605938
chembl3605938
CHEMBL3605936
chembl3605936
CHEMBL3605966
chembl3605966
CHEMBL3605964
chembl3605964
CHEMBL3605962
chembl3605962
CHEMBL3605961
chembl3605961
CHEMBL3605960
chembl3605960
CHEMBL3605958
chembl3605958
CHEMBL3605965
chembl3605965
CHEMBL3605963
chembl3605963
CHEMBL3605959
chembl3605959
CHEMBL3605957
chembl3605957
CHEMBL3605955
chembl3605955
CHEMBL3605956
chembl3605956
CHEMBL3605954
chembl3605954
CHEMBL1709349
chembl1709349
CHEMBL3605950
chembl3605950
CHEMBL3605948
chembl3605948
CHEMBL3605953
chembl3605953
CHEMBL3605952
chembl3605952
CHEMBL3605951
chembl3605951
CHEMBL140061
chembl140061
CHEMBL3605949
chembl3605949
CHEMBL3605947
chembl3605947
CHEMBL3603862
chembl3603862
CHEMBL3605944
chembl3605944
CHEMBL3929979
chembl3929979
CHEMBL3605946
chembl3605946
CHEMBL3605945
chembl3605945
CHEMBL3915228
chembl3915228
CHEMBL3904558
chembl3904558
CHEMBL3971712
chembl3971712
CHEMBL1611598
chembl1611598
CHEMBL3983375
chembl3983375
CHEMBL1582716
chembl1582716
CHEMBL3936357
chembl3936357
CHEMBL3922548
chembl3922548
CHEMBL3931464
chembl3931464
CHEMBL1381448
chembl1381448
CHEMBL3903482
chembl3903482
CHEMBL1388440
chembl1388440
CHEMBL3964195
chembl3964195
CHEMBL1375204
chembl1375204
CHEMBL1424505
chembl1424505
CHEMBL4102557
chembl4102557
CHEMBL4104103
chembl4104103
CHEMBL4078312
chembl4078312
CHEMBL4096360
chembl4096360
CHEMBL4086196
chembl4086196
CHEMBL4101686
chembl4101686
CHEMBL4075001
chembl4075001
CHEMBL4093953
chembl4093953
CHEMBL4097289
chembl4097289
CHEMBL4066400
chembl4066400
CHEMBL4085774
chembl4085774
CHEMBL4071760
chembl4071760
CHEMBL4070099
chembl4070099
CHEMBL4103702
chembl4103702
CHEMBL4065917
chembl4065917
CHEMBL4088220
chembl4088220
CHEMBL4095950
chembl4095950
CHEMBL4066944
chembl4066944
CHEMBL4096869
chembl4096869
CHEMBL4076738
chembl4076738
CHEMBL4077911
chembl4077911
CHEMBL4069653
chembl4069653
CHEMBL4097823
chembl4097823
CHEMBL4074066
chembl4074066
CHEMBL4080847
chembl4080847
CHEMBL4060407
chembl4060407
CHEMBL4087907
chembl4087907
CHEMBL4076088
chembl4076088
CHEMBL4070162
chembl4070162
CHEMBL4092207
chembl4092207
CHEMBL4104156
chembl4104156
CHEMBL4062938
chembl4062938
CHEMBL4084601
chembl4084601
CHEMBL4074312
chembl4074312
CHEMBL4101056
chembl4101056
CHEMBL4100095
chembl4100095
CHEMBL4082086
chembl4082086
CHEMBL4070517
chembl4070517
CHEMBL4096752
chembl4096752
CHEMBL4092341
chembl4092341
CHEMBL4071562
chembl4071562
CHEMBL4097685
chembl4097685
CHEMBL4069523
chembl4069523
CHEMBL4060851
chembl4060851
CHEMBL4099197
chembl4099197
CHEMBL4091463
chembl4091463
CHEMBL4162206
chembl4162206
CHEMBL4089049
chembl4089049
CHEMBL4081170
chembl4081170
CHEMBL4070549
chembl4070549
CHEMBL4208004
chembl4208004
CHEMBL4162911
chembl4162911
CHEMBL4212905
chembl4212905
CHEMBL4215326
chembl4215326
CHEMBL4470149
chembl4470149
CHEMBL4554522
chembl4554522
CHEMBL4558658
chembl4558658
CHEMBL4461581
chembl4461581
CHEMBL4442279
chembl4442279
CHEMBL4526979
chembl4526979
CHEMBL4582042
chembl4582042
CHEMBL4470318
chembl4470318
CHEMBL4527662
chembl4527662
CHEMBL4537137
chembl4537137
CHEMBL4574840
chembl4574840
CHEMBL4450778
chembl4450778
CHEMBL4469152
chembl4469152
CHEMBL4547807
chembl4547807
CHEMBL4457636
chembl4457636
CHEMBL4454542
chembl4454542
CHEMBL4591248
chembl4591248
CHEMBL4171551
chembl4171551
CHEMBL2326941
chembl2326941
CHEMBL4878570
chembl4878570
CHEMBL5070897
chembl5070897
CHEMBL5093179
chembl5093179
CHEMBL2171452
chembl2171452
CHEMBL5075218
chembl5075218
VENGLUSTAT
chembl4297611
SINEFUNGIN
chembl1214186
CHEMBL1091913
chembl1091913
CHEMBL5202371
chembl5202371
CHEMBL5173553
chembl5173553
CHEMBL5187166
chembl5187166
CHEMBL5269562
chembl5269562
CHEMBL5276042
chembl5276042
CHEMBL5285340
chembl5285340
CHEMBL5403284
chembl5403284
CHEMBL5410162
chembl5410162
CHEMBL5414585
chembl5414585
CHEMBL5425605
chembl5425605
CHEMBL4559961
chembl4559961
CHEMBL5415008
chembl5415008
CHEMBL5087479
chembl5087479
CHEMBL5612550
chembl5612550
CHEMBL5085070
chembl5085070
CHEMBL5573027
chembl5573027
CHEMBL4856110
chembl4856110
CHEMBL5646580
chembl5646580
CHEMBL3763271
chembl3763271
CHEMBL5647342
chembl5647342
CHEMBL5647573
chembl5647573
CHEMBL5647301
chembl5647301
CHEMBL5639460
chembl5639460
CHEMBL5639657
chembl5639657
CHEMBL5639617
chembl5639617
CHEMBL5647000
chembl5647000
CHEMBL5647468
chembl5647468
CHEMBL5639675
chembl5639675
CHEMBL5647209
chembl5647209
CHEMBL5646532
chembl5646532
CHEMBL5187396
chembl5187396
VALEMETOSTAT
chembl4597193
disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.
No matching rows
Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.
Mirror rows whose text fields mention this symbol — registry context only.
No matching live evidence found
Populate clinical_trials via the registry enrichment flow; this panel matches the symbol token in titles, conditions, or interventions.
Repurposing signal rows for drugs linked to this target via drug_targets.
No research signals for linked drugs
Run the deterministic signal builder after drug_targets and source rows are present.
Structured rows with negative evidence_direction on disease–drug or signal tables.
No negative-direction rows
When structured evidence includes explicit negative direction fields, they surface here for oncology review.
No ClinicalTrials.gov mirror rows mention this symbol in titles, conditions, or interventions (within the loaded window).
- chembl: 193
- opentargets: 1
Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.
Disease contexts
0
Linked drugs
0
Linked in dataset
0
Research signals
0
Doctor-discussion candidate and related tags are descriptive only.
Signals list: Live structured evidence (Supabase)
No matching live evidence found
When repurposing_signal rows reference this marker via linked drugs, summaries appear here.