Target detail
AR
androgen receptor
Data: Live structured evidence (Supabase)
Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).
Display name: androgen receptor
Aliases: AR, androgen receptor
Type / organism: protein_coding · Homo sapiens
Source: opentargets · ENSG00000169083
Index freshness: last_synced_at 2026-05-15T17:52:45.848+00:00 · updated 2026-05-15T17:52:46.203509+00:00
Limitations & build flags
- Read-only structured navigator
- No clinical outcome benefit inferred
- Trial presence does not imply success
- Drug identity may require normalization
- Terminated/withdrawn trials must remain visible
This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.
Connectors represented in loaded rows for AR. Empty groups mean no matching rows — not a claim about biology or clinical use.
- ClinicalTrials.govLive when indexed
Registry mirror rows in clinical_trials when operators run the CT.gov enrichment CLI — browser never calls the registry directly.
- Open TargetsLive when indexed
Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).
Rows from disease_target_evidence for this symbol.
glioblastoma
literature · opentargets
Drug records tied via drug_targets — mechanistic linkage only.
No linked drug rows
When drug_targets and drugs rows exist for this symbol, they are listed here.
disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.
No matching rows
Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.
Mirror rows whose text fields mention this symbol — registry context only.
NCT01721577 — Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00365222 — Phase II Study of Temozolomide in Newly Diagnosed Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT02669173 — Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05053880 — A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT00782756 — Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03660761 — Apatinib in Recurrent or Refractory Intracranial Central Nervous System Malignant Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01808820 — Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00979862 — Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00761280 — Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT02864368 — Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT01700569 — Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00293423 — GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05775458 — Glutamate Excitotoxicity and Its Role in Glioblastoma Biology
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05686798 — Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05768087 — Escalated Dose Proton Therapy Within the Multimodality Treatment of Glioblastoma Patients
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00813943 — Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05756985 — Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT07389278 — Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT02223052 — Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06831526 — Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT03332355 — Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT04051606 — Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01582269 — A Study in Recurrent Glioblastoma (GB)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05333588 — The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT05909618 — Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT02502708 — Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02177578 — Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT04743310 — Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04209790 — Neoadjuvant Chemoradiation for Resectable Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00797940 — Convection Enhanced Localized Administration of PRX321 With Real-time Imaging for Therapy of Recurrent Glioblastoma (CLARITY-1)
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT01124240 — Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT00068510 — Vaccine Therapy in Treating Patients With Malignant Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02968940 — Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03034135 — Safety, Tolerability and Efficacy of Disulfiram and Copper Gluconate in Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03477513 — Personalized Radiation Therapy for GBM
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT06059690 — Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT03115333 — DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT07552233 — NK Cell Therapy for Malignant Solid Brain Tumors
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT01631552 — Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00387933 — Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00253487 — Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed Gliomas
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04444427 — Evaluation of GLR2007 for Advanced Solid Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01849146 — Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02698280 — Bevacizumab and Nimustine in Patients With Recurrent High Grade Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00104091 — Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00704080 — A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01790503 — A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04657146 — Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma
Status: SUSPENDED · clinicaltrials.gov
Open trials hubNCT03251027 — Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT07413796 — Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT03107780 — Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT05399524 — Functional and Ultrasound Guided Resection of Glioblastoma
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT04180046 — Utility of Primary Glioblastoma Cell Lines
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT03626896 — Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03033524 — Trial to Evaluate the Safety of TTAC-0001(Tanibirumab) in Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00376103 — Radiation Boost for Newly Diagnosed Glioblastoma Multiforme
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00433381 — Bevacizumab and Irinotecan or Temozolomide in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02433392 — Study of Intraparenchymal Therapy as Adjunct Therapy in Patients With Recurrent, Resectable Glioblastoma Multiforme.
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00590681 — Bevacizumab and Temozolomide Following Radiation and Chemotherapy for Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00255671 — Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02366728 — DC Migration Study for Newly-Diagnosed GBM
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00624728 — Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06672575 — A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00071539 — Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01011231 — Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Imaging (MRI) Spectroscopy for Recurrent Glioma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT03705351 — Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT01499251 — Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00584883 — A Phase I Study of ABT 510 for Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02977780 — INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT02104882 — INTRAGO-Intraoperative Radiotherapy for Glioblastoma - a Phase I/II Study
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02685605 — Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT01985256 — Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01607905 — Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06072586 — A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05653622 — Simultaneous Integrated Boost FDOPA Positron Emission Tomography (PET) Guided in Patients With Partially- or Non-operated Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT02179086 — Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT00509431 — Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04671459 — TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT06665724 — Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01865162 — Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02661282 — Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02311920 — Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT07365280 — Neoantigen-Pulsed Autologous Dendritic Cell Vaccine Combined With Temozolomide for Newly Diagnosed Glioblastoma
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT03176160 — LITT Palliative Treatment for Patients With Malignant Gliomas
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT02465268 — Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01925573 — Optune(NOVOTTF-100A)+ Bevacizumab+ Hypofractionated Stereotactic Irradiation Bevacizumab-Naive Recurrent Glioblastoma (GCC 1344)
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT03596086 — HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00006246 — Busulfan in Treating Children and Adolescents With Refractory CNS Cancer
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05106296 — Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00039494 — Erlotinib and Temozolomide With Radiation Therapy in Treating Patients With Glioblastoma Multiforme or Other Brain Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00979173 — Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02800486 — Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT01317888 — Access Protocol for MAB-425 Radiolabeled With I-125 for High Grade Gliomas
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT04221503 — Niraparib/TTFields in GBM
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT01702792 — Derivation of Tumor Specific Hybridomas
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT03463265 — Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00727506 — BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05956821 — Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT06346821 — Tumor Treating Fields for Newly Diagnosed Glioblastoma: Two Emulated Trials With Chinese Multi-Hospital Based Real-World Data
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02394665 — Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00345163 — A Study to Evaluate Bevacizumab Alone or in Combination With Irinotecan for Treatment of Glioblastoma Multiforme (BRAIN)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01062399 — Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00003567 — Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT04547621 — HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBM
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT00516607 — Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT07138001 — Phase 2 Clinical Trial of KH617
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT06492486 — Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT03603379 — Doxorubicin-loaded Anti-EGFR-immunoliposomes (C225-ILs-dox) in High-grade Gliomas
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00752323 — Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06160596 — Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT02815410 — Validation of the Role of Levetiracetam for Newly Diagnosed GBM Patients
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT04863950 — Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT04600817 — A Study to Evaluate the Efficacy and Safety of TJ107 in Lympopenic Patients With Newly Diagnosed Glioblastoma Who Completed Standard Concurrent Chemoradiotherapy (CCRT)
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT01478854 — Neural Progenitor Cell Sparing Radiation Therapy Plus Temozolomide
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT07387666 — Imaging Acetadote Metabolism in Glioblastoma
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT05765812 — A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT01100177 — Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02431572 — A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or Immunotherapy
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02678975 — Disulfiram in Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01833273 — Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01699269 — Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04547855 — Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT07493447 — Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT05708352 — A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT06954636 — Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00436436 — O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT07457307 — Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT07141732 — Combined Treatment of Patients With Newly Diagnosed Glioblastoma Using the Xoft® Axxent® Electronic Brachytherapy (eBx®) System for Intraoperative Balloon Electronic Brachytherapy
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT03633552 — Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT04945148 — Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT01013285 — Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06710249 — Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT04656535 — AB154 Combined With AB122 for Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT02129335 — Stress, Exercise Behavior and Survival in Patients With Newly Diagnosed Glioblastoma and in a Close Partner
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT02520635 — Supra-early Post-Surgery Chemotherapy in the Treatment on GBM Patients
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT06558214 — OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00402116 — Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04440358 — Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01478178 — Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02631655 — POSitron Emission Imaging Using 18F-FDOPA in Neurooncology
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT07485049 — BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT04143425 — Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01989884 — An Efficacy Study Of Ortataxel In Recurrent Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03922984 — Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02664363 — EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT03687034 — A Study of the Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastoma
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT01222221 — Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03618667 — GC1118 in Recurrent Glioblastoma Patients With High EGFR Amplification
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04854044 — ONC201 and Radiation Therapy Before Surgery for the Treatment of Recurrent Glioblastoma
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT00974987 — Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05460507 — Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05753007 — A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00010036 — Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03405792 — Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT01009307 — Study of Blood and Cheek Cell Samples From Patients With Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04218019 — Effect of Timing of Tumor-Treating Fields Plus Short-Course Radiation
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT05879367 — Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT07521657 — Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT07052877 — The Effect of Glioblastoma PSMA Expression Following Tumour VEGF Blockade From Bevacizumab
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT02283944 — TMS Electrochemotherapy for Glioblastoma Multiforme
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT02658981 — Anti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04590664 — Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00430911 — Radiotherapy for Malignant Astrocytomas in the Elderly
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04959500 — Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT04222309 — Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)
Status: SUSPENDED · clinicaltrials.gov
Open trials hubNCT02253212 — Safety of BBB Opening With the SonoCloud
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04846257 — Specific Preoperative Dynamic Contrast-enhanced MRI Semi-quantitative Markers Can Correlate With Vascularity in Specific Areas of the Glioblastoma Tissue and Predict Recurrence
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06556563 — EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05241392 — Safety and Efficacy Study of Anti-B7-H3 CAR-T Cell Therapy for Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT00609999 — Ph I Dasatinib + Erlotinib in Recurrent MG
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00562419 — CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT03897491 — PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT03367715 — Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02152748 — Disease Progression and Treatment-induced Alterations in Glioblastoma
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT03275558 — Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of Glioblastoma
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT03466450 — Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03048240 — INtraoperative photoDYnamic Therapy of GliOblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04541225 — Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT05267106 — Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00823797 — Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02717962 — Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03630289 — Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT03370926 — FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT01782976 — Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT00004024 — Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02649582 — Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT00895180 — Ramucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05879120 — Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent Glioblastoma
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT00939991 — Suberoylanilide Hydroxamic Acid (SAHA), Bevacizumab, Daily Temozolomide for Recurrent Malignant Gliomas
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04474353 — Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00643097 — Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT02617589 — An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03452579 — Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBM
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT03403803 — Prognosis and Therapeutic Biomarkers for Glioblastoma Patients
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00884741 — Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00720356 — Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04991870 — Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05977322 — A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00305656 — AZD2171 in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06973096 — CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT02444546 — Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06359379 — Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT00253669 — Risk Factors for Developing a Blood Clot in Patients Who Are Undergoing Cancer Treatment for Newly Diagnosed Gliomas
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04047303 — CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT04908176 — A Drug-drug Interaction Study of Avapritinib and Midazolam
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00095940 — Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT05131815 — The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT03152318 — A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT06146725 — The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00003185 — Biological Therapy in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04536649 — Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma.
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT01870726 — Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT02575027 — Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01342757 — Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT01430351 — Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT05843253 — Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT01109095 — CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04552886 — Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastoma
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT04135807 — Implantable Microdevice In Primary Brain Tumors
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT03970447 — A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT05131763 — NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors
Status: UNKNOWN · clinicaltrials.gov
Open trials hubNCT02974621 — Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT00916409 — Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06501911 — A Study of Bicalutamide With Brain Re-irradiation to Treat Recurrent/Progressive High Grade Glioma
Status: WITHDRAWN · clinicaltrials.gov
Open trials hubNCT05557292 — RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma
Status: TERMINATED · clinicaltrials.gov
Open trials hubNCT07284628 — Vortioxetine for Newly Diagnosed Glioblastoma
Status: NOT_YET_RECRUITING · clinicaltrials.gov
Open trials hubNCT01873469 — Impact of [11C]-Methionine PET/MRI for Individual Tailoring Postoperative Radiochemotherapy for Glioblastoma Multiforme
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT00723827 — Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)
Status: COMPLETED · clinicaltrials.gov
Open trials hubNCT06499831 — 18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas
Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov
Open trials hubNCT06850766 — The Feasibility and Efficacy of Dose Timing (Morning vs Evening) of Temozolomide in the Treatment of Glioblastoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT06264388 — DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma
Status: RECRUITING · clinicaltrials.gov
Open trials hubNCT00499473 — Sunitinib in Treating Patients With Recurrent Malignant Gliomas
Status: COMPLETED · clinicaltrials.gov
Open trials hubRepurposing signal rows for drugs linked to this target via drug_targets.
No research signals for linked drugs
Run the deterministic signal builder after drug_targets and source rows are present.
Structured rows with negative evidence_direction on disease–drug or signal tables.
No negative-direction rows
When structured evidence includes explicit negative direction fields, they surface here for oncology review.
- clinicaltrials.gov: 235
- opentargets: 1
Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.
Disease contexts
0
Linked drugs
0
Linked in dataset
0
Research signals
0
Doctor-discussion candidate and related tags are descriptive only.
Signals list: Live structured evidence (Supabase)
No matching live evidence found
When repurposing_signal rows reference this marker via linked drugs, summaries appear here.