Target detail
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5
Data: Live structured evidence (Supabase)
Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).
Display name: ADAM metallopeptidase with thrombospondin type 1 motif 5
Aliases: ADAMTS5, ADAM metallopeptidase with thrombospondin type 1 motif 5
Type / organism: protein_coding · Homo sapiens
Source: opentargets · ENSG00000154736
Index freshness: last_synced_at 2026-05-15T18:33:22.137+00:00 · updated 2026-05-15T18:33:22.603723+00:00
Limitations & build flags
- Read-only structured navigator
- No clinical outcome benefit inferred
- Trial presence does not imply success
- Drug identity may require normalization
- Terminated/withdrawn trials must remain visible
This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.
Connectors represented in loaded rows for ADAMTS5. Empty groups mean no matching rows — not a claim about biology or clinical use.
- Open TargetsLive when indexed
Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).
- ChEMBLLive when indexed
Drug–target and related enrichment rows when operators run enrich:chembl (server/CLI only).
Rows from disease_target_evidence for this symbol.
glioblastoma
literature · opentargets
Drug records tied via drug_targets — mechanistic linkage only.
CHEMBL1078322
chembl1078322
CHEMBL514714
chembl514714
CHEMBL2437154
chembl2437154
CHEMBL1766913
chembl1766913
CHEMBL1767009
chembl1767009
CHEMBL197842
chembl197842
CHEMBL1766910
chembl1766910
CHEMBL2163738
chembl2163738
CHEMBL1767008
chembl1767008
CHEMBL2437162
chembl2437162
CHEMBL1807393
chembl1807393
CHEMBL475867
chembl475867
CHEMBL397040
chembl397040
CHEMBL2348089
chembl2348089
CHEMBL2348110
chembl2348110
CHEMBL233333
chembl233333
CHEMBL3104666
chembl3104666
CHEMBL1766917
chembl1766917
CHEMBL476835
chembl476835
CHEMBL391124
chembl391124
CHEMBL2164085
chembl2164085
CHEMBL515272
chembl515272
CHEMBL237366
chembl237366
CHEMBL1767006
chembl1767006
CHEMBL472143
chembl472143
CHEMBL2346679
chembl2346679
CHEMBL2348102
chembl2348102
CHEMBL481895
chembl481895
CHEMBL1807402
chembl1807402
CHEMBL1784349
chembl1784349
CHEMBL1270177
chembl1270177
CHEMBL1270467
chembl1270467
CHEMBL2164078
chembl2164078
CHEMBL1784369
chembl1784369
CHEMBL2348116
chembl2348116
CHEMBL481505
chembl481505
CHEMBL1784338
chembl1784338
CHEMBL475435
chembl475435
CHEMBL460533
chembl460533
CHEMBL2164102
chembl2164102
CHEMBL481320
chembl481320
CHEMBL1079172
chembl1079172
CHEMBL2164112
chembl2164112
CHEMBL1784341
chembl1784341
CHEMBL1784365
chembl1784365
CHEMBL480766
chembl480766
CHEMBL2348090
chembl2348090
CHEMBL2437161
chembl2437161
CHEMBL515499
chembl515499
CHEMBL2164108
chembl2164108
CHEMBL396217
chembl396217
CHEMBL472144
chembl472144
CHEMBL230834
chembl230834
CHEMBL2164107
chembl2164107
CHEMBL474201
chembl474201
CHEMBL521411
chembl521411
CHEMBL1784344
chembl1784344
CHEMBL2348073
chembl2348073
CHEMBL2164118
chembl2164118
CHEMBL230408
chembl230408
CHEMBL475265
chembl475265
CHEMBL514972
chembl514972
CHEMBL2337692
chembl2337692
CHEMBL2347849
chembl2347849
CHEMBL1615187
chembl1615187
CHEMBL1269853
chembl1269853
CHEMBL438674
chembl438674
CHEMBL1940315
chembl1940315
CHEMBL473434
chembl473434
CHEMBL2348069
chembl2348069
CHEMBL231754
chembl231754
CHEMBL1784337
chembl1784337
CHEMBL393651
chembl393651
CHEMBL2164099
chembl2164099
CHEMBL2437164
chembl2437164
CHEMBL2164095
chembl2164095
CHEMBL237367
chembl237367
CHEMBL1078281
chembl1078281
CHEMBL2348076
chembl2348076
CHEMBL187092
chembl187092
CHEMBL475770
chembl475770
CHEMBL1910449
chembl1910449
CHEMBL2337694
chembl2337694
CHEMBL495507
chembl495507
CHEMBL2348112
chembl2348112
CHEMBL2348085
chembl2348085
CHEMBL1766908
chembl1766908
CHEMBL2337689
chembl2337689
CHEMBL2164084
chembl2164084
CHEMBL229990
chembl229990
CHEMBL230726
chembl230726
CHEMBL481506
chembl481506
CHEMBL473326
chembl473326
CHEMBL230618
chembl230618
CHEMBL1767007
chembl1767007
CHEMBL235890
chembl235890
CHEMBL476640
chembl476640
CHEMBL1767004
chembl1767004
CHEMBL1784353
chembl1784353
CHEMBL2164080
chembl2164080
CHEMBL478473
chembl478473
CHEMBL179552
chembl179552
CHEMBL477853
chembl477853
CHEMBL498598
chembl498598
CHEMBL1766922
chembl1766922
CHEMBL466118
chembl466118
CHEMBL2337690
chembl2337690
CHEMBL2348084
chembl2348084
CHEMBL474069
chembl474069
CHEMBL482362
chembl482362
CHEMBL2348097
chembl2348097
CHEMBL1270070
chembl1270070
CHEMBL2337691
chembl2337691
CHEMBL1784366
chembl1784366
ILOMASTAT
chembl19611
CHEMBL448604
chembl448604
CHEMBL2348105
chembl2348105
CHEMBL1079122
chembl1079122
CHEMBL481896
chembl481896
CHEMBL198778
chembl198778
CHEMBL2437152
chembl2437152
CHEMBL231962
chembl231962
CHEMBL236106
chembl236106
CHEMBL237149
chembl237149
CHEMBL475029
chembl475029
CHEMBL394936
chembl394936
CHEMBL2164105
chembl2164105
CHEMBL481899
chembl481899
CHEMBL230725
chembl230725
CHEMBL3104664
chembl3104664
CHEMBL477040
chembl477040
CHEMBL2348082
chembl2348082
CHEMBL2164083
chembl2164083
CHEMBL1784362
chembl1784362
CHEMBL482360
chembl482360
CHEMBL400202
chembl400202
CHEMBL394026
chembl394026
CHEMBL230835
chembl230835
CHEMBL2337696
chembl2337696
CHEMBL2164103
chembl2164103
CHEMBL475668
chembl475668
CHEMBL2164106
chembl2164106
CHEMBL2348074
chembl2348074
CHEMBL2348108
chembl2348108
CHEMBL475771
chembl475771
CHEMBL395985
chembl395985
CHEMBL443680
chembl443680
CHEMBL236317
chembl236317
CHEMBL475460
chembl475460
CHEMBL1910472
chembl1910472
CHEMBL478126
chembl478126
CHEMBL474795
chembl474795
CHEMBL1807399
chembl1807399
CHEMBL1807405
chembl1807405
CHEMBL391123
chembl391123
CHEMBL1269962
chembl1269962
CHEMBL482073
chembl482073
CHEMBL473433
chembl473433
CHEMBL393991
chembl393991
CHEMBL1766907
chembl1766907
CHEMBL2437158
chembl2437158
CHEMBL514963
chembl514963
CHEMBL1766909
chembl1766909
CHEMBL236318
chembl236318
CHEMBL2448145
chembl2448145
CHEMBL476667
chembl476667
CHEMBL1784339
chembl1784339
CHEMBL2348111
chembl2348111
CHEMBL2348066
chembl2348066
CHEMBL2348101
chembl2348101
CHEMBL1766920
chembl1766920
CHEMBL523034
chembl523034
CHEMBL238012
chembl238012
CHEMBL208009
chembl208009
CHEMBL233132
chembl233132
CHEMBL461719
chembl461719
CHEMBL1078623
chembl1078623
CHEMBL230620
chembl230620
CHEMBL231738
chembl231738
CHEMBL1767005
chembl1767005
CHEMBL1766896
chembl1766896
CHEMBL482074
chembl482074
CHEMBL2164090
chembl2164090
CHEMBL1766906
chembl1766906
CHEMBL1784359
chembl1784359
CHEMBL2164088
chembl2164088
CHEMBL2348100
chembl2348100
CHEMBL1766921
chembl1766921
CHEMBL473637
chembl473637
CHEMBL2437150
chembl2437150
CHEMBL1078280
chembl1078280
CHEMBL1784363
chembl1784363
CHEMBL396206
chembl396206
CHEMBL391928
chembl391928
CHEMBL2437186
chembl2437186
CHEMBL444891
chembl444891
CHEMBL1940308
chembl1940308
CHEMBL230895
chembl230895
CHEMBL1767014
chembl1767014
CHEMBL1270466
chembl1270466
disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.
No matching rows
Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.
Mirror rows whose text fields mention this symbol — registry context only.
No matching live evidence found
Populate clinical_trials via the registry enrichment flow; this panel matches the symbol token in titles, conditions, or interventions.
Repurposing signal rows for drugs linked to this target via drug_targets.
No research signals for linked drugs
Run the deterministic signal builder after drug_targets and source rows are present.
Structured rows with negative evidence_direction on disease–drug or signal tables.
No negative-direction rows
When structured evidence includes explicit negative direction fields, they surface here for oncology review.
No ClinicalTrials.gov mirror rows mention this symbol in titles, conditions, or interventions (within the loaded window).
- chembl: 500
- opentargets: 1
Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.
Disease contexts
0
Linked drugs
0
Linked in dataset
0
Research signals
0
Doctor-discussion candidate and related tags are descriptive only.
Signals list: Live structured evidence (Supabase)
No matching live evidence found
When repurposing_signal rows reference this marker via linked drugs, summaries appear here.