Target detail
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
Data: Live structured evidence (Supabase)
Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).
Display name: ADAM metallopeptidase with thrombospondin type 1 motif 1
Aliases: ADAMTS1, ADAM metallopeptidase with thrombospondin type 1 motif 1
Type / organism: protein_coding · Homo sapiens
Source: opentargets · ENSG00000154734
Index freshness: last_synced_at 2026-05-15T17:39:29.338+00:00 · updated 2026-05-15T17:39:29.684076+00:00
Limitations & build flags
- Read-only structured navigator
- No clinical outcome benefit inferred
- Trial presence does not imply success
- Drug identity may require normalization
- Terminated/withdrawn trials must remain visible
This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.
Connectors represented in loaded rows for ADAMTS1. Empty groups mean no matching rows — not a claim about biology or clinical use.
- Open TargetsLive when indexed
Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).
- ChEMBLLive when indexed
Drug–target and related enrichment rows when operators run enrich:chembl (server/CLI only).
Rows from disease_target_evidence for this symbol.
glioblastoma
literature · opentargets
Drug records tied via drug_targets — mechanistic linkage only.
CHEMBL5592306
chembl5592306
CHEMBL4874226
chembl4874226
CHEMBL4850670
chembl4850670
CHEMBL4873384
chembl4873384
CHEMBL5593176
chembl5593176
CHEMBL1940315
chembl1940315
CHEMBL4846457
chembl4846457
CHEMBL187092
chembl187092
CHEMBL473326
chembl473326
CHEMBL4877087
chembl4877087
CHEMBL208009
chembl208009
CHEMBL1940308
chembl1940308
CHEMBL4876864
chembl4876864
CHEMBL207305
chembl207305
CHEMBL2164094
chembl2164094
CHEMBL2164122
chembl2164122
CHEMBL4863614
chembl4863614
CHEMBL4877662
chembl4877662
CHEMBL4876618
chembl4876618
CHEMBL253275
chembl253275
CHEMBL495502
chembl495502
CHEMBL500351
chembl500351
CHEMBL5589804
chembl5589804
CHEMBL4862188
chembl4862188
CHEMBL2164113
chembl2164113
CHEMBL4856943
chembl4856943
CHEMBL4856883
chembl4856883
CHEMBL2164121
chembl2164121
CHEMBL4868710
chembl4868710
ALDUMASTAT
chembl4650334
CHEMBL4854306
chembl4854306
CHEMBL2164120
chembl2164120
CHEMBL2164111
chembl2164111
disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.
No matching rows
Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.
Mirror rows whose text fields mention this symbol — registry context only.
No matching live evidence found
Populate clinical_trials via the registry enrichment flow; this panel matches the symbol token in titles, conditions, or interventions.
Repurposing signal rows for drugs linked to this target via drug_targets.
No research signals for linked drugs
Run the deterministic signal builder after drug_targets and source rows are present.
Structured rows with negative evidence_direction on disease–drug or signal tables.
No negative-direction rows
When structured evidence includes explicit negative direction fields, they surface here for oncology review.
No ClinicalTrials.gov mirror rows mention this symbol in titles, conditions, or interventions (within the loaded window).
- chembl: 33
- opentargets: 1
Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.
Disease contexts
0
Linked drugs
0
Linked in dataset
0
Research signals
0
Doctor-discussion candidate and related tags are descriptive only.
Signals list: Live structured evidence (Supabase)
No matching live evidence found
When repurposing_signal rows reference this marker via linked drugs, summaries appear here.