Target detail
ADAM9
ADAM metallopeptidase domain 9
Data: Live structured evidence (Supabase)
Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).
Display name: ADAM metallopeptidase domain 9
Aliases: ADAM9, ADAM metallopeptidase domain 9
Type / organism: protein_coding · Homo sapiens
Source: opentargets · ENSG00000168615
Index freshness: last_synced_at 2026-05-15T17:54:29.426+00:00 · updated 2026-05-15T17:54:29.824126+00:00
Limitations & build flags
- Read-only structured navigator
- No clinical outcome benefit inferred
- Trial presence does not imply success
- Drug identity may require normalization
- Terminated/withdrawn trials must remain visible
This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.
Connectors represented in loaded rows for ADAM9. Empty groups mean no matching rows — not a claim about biology or clinical use.
- Open TargetsLive when indexed
Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).
- ChEMBLLive when indexed
Drug–target and related enrichment rows when operators run enrich:chembl (server/CLI only).
- CANTI signal builderLive when indexed
Deterministic repurposing-signal rows produced by the in-repo signal builder when operators run the build pipeline.
Rows from disease_target_evidence for this symbol.
glioblastoma
literature · opentargets
Drug records tied via drug_targets — mechanistic linkage only.
CHEMBL172722
chembl172722
CHEMBL368857
chembl368857
CHEMBL3648907
chembl3648907
CHEMBL173686
chembl173686
CHEMBL368205
chembl368205
CHEMBL172886
chembl172886
CHEMBL4873384
chembl4873384
CHEMBL173235
chembl173235
CHEMBL3648903
chembl3648903
CHEMBL3392650
chembl3392650
CHEMBL366034
chembl366034
CHEMBL355797
chembl355797
CHEMBL4215407
chembl4215407
CHEMBL171962
chembl171962
CHEMBL4102106
chembl4102106
CHEMBL172415
chembl172415
CHEMBL173316
chembl173316
ILOMASTAT
chembl19611
GRASSYSTATIN C
chembl569445
CHEMBL171292
chembl171292
CHEMBL171986
chembl171986
APRATASTAT
chembl206815
GRASSYSTATIN A
chembl567893
CHEMBL353536
chembl353536
CHEMBL433981
chembl433981
CHEMBL3966632
chembl3966632
CHEMBL3935135
chembl3935135
CHEMBL4167357
chembl4167357
CHEMBL188414
chembl188414
CHEMBL434567
chembl434567
CHEMBL3704919
chembl3704919
CHEMBL3648905
chembl3648905
CHEMBL3941484
chembl3941484
CHEMBL173754
chembl173754
CHEMBL174014
chembl174014
CHEMBL170315
chembl170315
CHEMBL170429
chembl170429
CHEMBL365261
chembl365261
CHEMBL3704903
chembl3704903
CHEMBL367710
chembl367710
CHEMBL4208519
chembl4208519
CHEMBL172249
chembl172249
CHEMBL497985
chembl497985
CHEMBL173326
chembl173326
CHEMBL539171
chembl539171
CHEMBL4215451
chembl4215451
CHEMBL3648902
chembl3648902
CHEMBL366478
chembl366478
CHEMBL3704910
chembl3704910
CHEMBL172548
chembl172548
CHEMBL418655
chembl418655
CHEMBL3648893
chembl3648893
CHEMBL3897740
chembl3897740
CHEMBL425316
chembl425316
CHEMBL3643916
chembl3643916
CHEMBL172885
chembl172885
CHEMBL436049
chembl436049
CHEMBL3648906
chembl3648906
CHEMBL3648904
chembl3648904
CHEMBL177072
chembl177072
CHEMBL361087
chembl361087
CHEMBL4214929
chembl4214929
CHEMBL173027
chembl173027
PEPSTATIN
chembl296588
CHEMBL3959985
chembl3959985
CHEMBL173744
chembl173744
CHEMBL4210512
chembl4210512
GRASSYSTATIN B
chembl568553
Symplostatin 5
chembl2338554
CHEMBL4854306
chembl4854306
CHEMBL172181
chembl172181
CHEMBL3643914
chembl3643914
CHEMBL175164
chembl175164
CHEMBL174315
chembl174315
CHEMBL173846
chembl173846
CHEMBL1078396
chembl1078396
disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.
No matching rows
Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.
Mirror rows whose text fields mention this symbol — registry context only.
No matching live evidence found
Populate clinical_trials via the registry enrichment flow; this panel matches the symbol token in titles, conditions, or interventions.
Repurposing signal rows for drugs linked to this target via drug_targets.
Repurposing research signal · APRATASTAT · v0.1
Deterministic research signal for APRATASTAT. Aggregate template score 55 (not a clinical endpoint). Contributing canonical sources observed in this rollup: chembl, opentargets. No failed-repoDB or terminated-trial penalty lines fired for this rollup. Missing relative to the Phase 8A template: glioma/brain-tumor–scoped ClinicalTrials.gov disease–drug evidence; repoDB-style disease–drug labels. This row requires clinical/research review before any operational use — not care-planning guidance, dose planning, or outcome-benefit claims.
Open signals hubStructured rows with negative evidence_direction on disease–drug or signal tables.
No negative-direction rows
When structured evidence includes explicit negative direction fields, they surface here for oncology review.
No ClinicalTrials.gov mirror rows mention this symbol in titles, conditions, or interventions (within the loaded window).
- chembl: 76
- opentargets: 1
- canti_signal_builder: 1
Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.
Disease contexts
0
Linked drugs
0
Linked in dataset
0
Research signals
0
Doctor-discussion candidate and related tags are descriptive only.
Signals list: Live structured evidence (Supabase)
Repurposing research signal · APRATASTAT · v0.1
Deterministic research signal for APRATASTAT. Aggregate template score 55 (not a clinical endpoint). Contributing canonical sources observed in this rollup: chembl, opentargets. No failed-repoDB or terminated-trial penalty lines fired for this rollup. Missing relative to the Phase 8A template: glioma/brain-tumor–scoped ClinicalTrials.gov disease–drug evidence; repoDB-style disease–drug labels. This row requires clinical/research review before any operational use — not care-planning guidance, dose planning, or outcome-benefit claims.
View signals hub