Back to targets

Target detail

ABO

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Data: Live structured evidence (Supabase)

Marker index metadata

Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).

Display name: ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Aliases: ABO, ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Type / organism: protein_coding · Homo sapiens

Source: opentargets · ENSG00000175164

Index freshness: last_synced_at 2026-05-15T17:45:14.374+00:00 · updated 2026-05-15T17:45:14.761466+00:00

Limitations & build flags

  • Read-only structured navigator
  • No clinical outcome benefit inferred
  • Trial presence does not imply success
  • Drug identity may require normalization
  • Terminated/withdrawn trials must remain visible
Target index (foundation)

This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.

Live structured evidence · sources

Connectors represented in loaded rows for ABO. Empty groups mean no matching rows — not a claim about biology or clinical use.

  • ClinicalTrials.govLive when indexed

    Registry mirror rows in clinical_trials when operators run the CT.gov enrichment CLI — browser never calls the registry directly.

  • Open TargetsLive when indexed

    Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).

  • ChEMBLLive when indexed

    Drug–target and related enrichment rows when operators run enrich:chembl (server/CLI only).

Open Targets · disease–target evidence

Rows from disease_target_evidence for this symbol.

glioblastoma

literature · opentargets

ChEMBL · linked drugs (drug_targets)

Drug records tied via drug_targets — mechanistic linkage only.

CHEMBL477507

chembl477507

Open drug

CHEMBL3596389

chembl3596389

Open drug

CHEMBL2326313

chembl2326313

Open drug

CHEMBL1235497

chembl1235497

Open drug
repoDB-style · approved-elsewhere discussion candidates

disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.

No matching rows

Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.

ClinicalTrials.gov · trial-matched options

Mirror rows whose text fields mention this symbol — registry context only.

NCT00979862 — Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT06059690 — Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells

Status: RECRUITING · clinicaltrials.gov

Open trials hub

NCT00255671 — Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT00624728 — Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP)

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT02179086 — Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Status: ACTIVE_NOT_RECRUITING · clinicaltrials.gov

Open trials hub

NCT02661282 — Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT02311920 — Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT07387666 — Imaging Acetadote Metabolism in Glioblastoma

Status: NOT_YET_RECRUITING · clinicaltrials.gov

Open trials hub

NCT01222221 — Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT01009307 — Study of Blood and Cheek Cell Samples From Patients With Glioma

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT02658981 — Anti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT01782976 — Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)

Status: WITHDRAWN · clinicaltrials.gov

Open trials hub

NCT00884741 — Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT02444546 — Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT00253669 — Risk Factors for Developing a Blood Clot in Patients Who Are Undergoing Cancer Treatment for Newly Diagnosed Gliomas

Status: COMPLETED · clinicaltrials.gov

Open trials hub

NCT00095940 — Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

Status: COMPLETED · clinicaltrials.gov

Open trials hub
CANTI signal builder · target-linked research signals

Repurposing signal rows for drugs linked to this target via drug_targets.

No research signals for linked drugs

Run the deterministic signal builder after drug_targets and source rows are present.

Caution / negative-evidence rows

Structured rows with negative evidence_direction on disease–drug or signal tables.

No negative-direction rows

When structured evidence includes explicit negative direction fields, they surface here for oncology review.

Missing evidence · row counts by source string
  • clinicaltrials.gov: 16
  • chembl: 4
  • opentargets: 1
Summary row (aggregated list)

Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.

Disease contexts

0

Linked drugs

0

Linked in dataset

0

Research signals

0

Evidence badges (illustrative)

Doctor-discussion candidate and related tags are descriptive only.

Appears in source landscapeLinked in datasetRequires oncology review
Linked research signals (list read)

Signals list: Live structured evidence (Supabase)

No matching live evidence found

When repurposing_signal rows reference this marker via linked drugs, summaries appear here.