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Target detail

ABCC8

ATP binding cassette subfamily C member 8

Data: Live structured evidence (Supabase)

Marker index metadata

Foundation row from public.targets — full Open Targets / ChEMBL preload remains a future operator job (Phase 8H+).

Display name: ATP binding cassette subfamily C member 8

Aliases: ABCC8, ATP binding cassette subfamily C member 8

Type / organism: protein_coding · Homo sapiens

Source: opentargets · ENSG00000006071

Index freshness: last_synced_at 2026-05-15T17:40:32.227+00:00 · updated 2026-05-15T17:40:32.570579+00:00

Disease hub (glioblastoma)Guided · ABCC8

Limitations & build flags

  • Read-only structured navigator
  • No clinical outcome benefit inferred
  • Trial presence does not imply success
  • Drug identity may require normalization
  • Terminated/withdrawn trials must remain visible
Target index (foundation)

This symbol is listed in public.targets (operator seed or future preload). Connector-backed sections below may still show empty states until ChEMBL / Open Targets / ClinicalTrials.gov mirror rows exist for this marker.

Glioblastoma disease hub·Guided lookup
Live structured evidence · sources

Connectors represented in loaded rows for ABCC8. Empty groups mean no matching rows — not a claim about biology or clinical use.

  • Open TargetsLive when indexed

    Disease–target evidence rows when operators run enrich:opentargets (GraphQL from trusted scripts only).

  • ChEMBLLive when indexed

    Drug–target and related enrichment rows when operators run enrich:chembl (server/CLI only).

Open Targets · disease–target evidence

Rows from disease_target_evidence for this symbol.

glioblastoma

literature · opentargets

ChEMBL · linked drugs (drug_targets)

Drug records tied via drug_targets — mechanistic linkage only.

BERBERRUBINE

chembl203135

Open drug

GLIQUIDONE

chembl383634

Open drug

CHEMBL186684

chembl186684

Open drug

CHEMBL437696

chembl437696

Open drug

REPAGLINIDE

chembl1272

Open drug

CHEMBL11697

chembl11697

Open drug

CHEMBL3330879

chembl3330879

Open drug

CHEMBL206717

chembl206717

Open drug

CHEMBL360610

chembl360610

Open drug

BERBERINE CHLORIDE

chembl12089

Open drug

CHEMBL3330880

chembl3330880

Open drug
repoDB-style · approved-elsewhere discussion candidates

disease_drug_evidence rows on linked drugs whose evidence_type suggests approved-elsewhere discussion context.

No matching rows

Import repoDB-compatible disease–drug evidence or add structured rows to surface discussion candidates here.

ClinicalTrials.gov · trial-matched options

Mirror rows whose text fields mention this symbol — registry context only.

No matching live evidence found

Populate clinical_trials via the registry enrichment flow; this panel matches the symbol token in titles, conditions, or interventions.

CANTI signal builder · target-linked research signals

Repurposing signal rows for drugs linked to this target via drug_targets.

No research signals for linked drugs

Run the deterministic signal builder after drug_targets and source rows are present.

Caution / negative-evidence rows

Structured rows with negative evidence_direction on disease–drug or signal tables.

No negative-direction rows

When structured evidence includes explicit negative direction fields, they surface here for oncology review.

Missing evidence · row counts by source string

No ClinicalTrials.gov mirror rows mention this symbol in titles, conditions, or interventions (within the loaded window).

  • chembl: 11
  • opentargets: 1
Summary row (aggregated list)

Structured evidence rows link this marker to cohort contexts when ingested — interpret as research context only.

Disease contexts

0

Linked drugs

0

Linked in dataset

0

Research signals

0

Evidence badges (illustrative)

Doctor-discussion candidate and related tags are descriptive only.

Appears in source landscapeLinked in datasetRequires oncology review
Linked research signals (list read)

Signals list: Live structured evidence (Supabase)

No matching live evidence found

When repurposing_signal rows reference this marker via linked drugs, summaries appear here.